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10.3280/RSF2016-002002

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[2] Osservatorio Nazionale sull’impiego dei Medicinali. L’uso dei farmaci in Italia. Rapporto Nazionale Gennaio-Settembre 2014. Roma: Agenzia Italiana del Farmaco; 2015.


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[4] Moncrieff J Antipsychotic Maintenance Treatment: Time to Rethink? Plos Medicine 2015; 12: e1001861.

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[6] Kirsch I. Antidepressants and placebo effect. Zeitschrift für Psychologie 2014; 222: 128-134.

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[7] Turner EH, Matthews AM, Linardatos E, Tell RA, Rosenthal R. Selective publication of antidepressant trials and its influence on apparent efficacy. New England Journal of Medicine 2008; 358: 252-260.

https://doi.org/10.1056/NEJMsa065779


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[9] Fournier JC, DeRubeis RJ, Hollon SD, Dimidjian S, Amsterdam JD, Shelton RC, et al. Antidepressant drug effects and depression severity: a patient-level meta-analysis. JAMA 2010; 303: 47-53.

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[11] Wunderink L, Nieboer RM, Wiersma D, Sytema S, Nienhuis FJ. Recovery in remitted first-episode psychosis at 7 years of follow-up of an early dose reduction/discontinuation or maintenance treatment strategy: Long-term follow-up of a 2-year randomized clinical trial. JAMA Psychiatry 2013, 70:913-920. [12] Alvarez-Jimenez M, O’Donoghue B, Thompson A, Gleeson JF, Bendall S, Gonzalez-Blanch C, et al. Beyond Clinical Remission in First Episode Psychosis: Thoughts on Antipsychotic Maintenance vs. Guided Discontinuation in the Functional Recovery Era. CNS drugs 2016; 1-12.


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[13] Coldham EL, Addington J, Addington D. Medication adherence of individuals with a first episode of psychosis. Acta Psychiatrica Scandinavica 2002; 106: 286-90.

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[15] Álvarez-Jiménez M, Hetrick SE, González-Blanch C, Gleeson JF, McGorry PD. Non-pharmacological management of antipsychotic-induced weight gain: systematic review and meta-analysis of randomised controlled trials. British Journal of Psychiatry 2008; 193: 101–7.

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[17] Lakka HM, Laaksonen DE, Lakka TA, Niskanen LK, Kumpusalo E, Tuomilehto J, Salonen JT. The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. JAMA 2002; 288: 2709-16.

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[18] Curtis J, Henry C, Watkins A, Newall H, Samaras K, Ward PB. Metabolic abnormalities in an early psychosis service: a retrospective, naturalistic crosssectional study. Early Intervention in Psychiatry 2011; 5: 108-14.

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[19] Kreyenbuhl J, Buchanan RW, Dickerson FB, Dixon LB, Schizophrenia Patient Outcomes Research Team (PORT). The Schizophrenia Patient Outcomes Research Team (PORT): updated treatment recommendations 2009. Schizophrenia Bulletin 2010; 36: 94-103.

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[21] Jones PB, Barnes TR, Davies L, et al. Randomized controlled trial of the effect on quality of life of second- vs first-generation antipsychotic drugs in schizophrenia: CostUtility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1). Archives of General Psychiatry 2006; 63: 1079–1087.

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[26] Deegan PE, Drake RE. Shared decision making and medication management in the recovery process. Psychiatric Services 2006; 57:1636-9.

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[27] Barbato A, Vallarino M, Rapisarda F, Lora A, Parabiaghi A, D’Avanzo B, et al. Do people with bipolar disorders have access to psychosocial treatments? A survey in Italy. International Journal of Social Psychiatry 2016; E-pub


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[28] Masciarri D, Natali D, Palazzari F. I farmaci da dentro. Presentato al Congresso Europeo della World Association for Psychosocial Rehabilitation 2015; Torino.


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[29] Progetto Contraria-Mente. Sospendere gli psicofarmaci. Manuale per la riduzione del danno. New York e Northampton: Icarus Project e Freedom Center; 2010.


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[30] Barbato A. La terapia farmacologica a lungo termine favorisce la guarigione dalle psicosi? In: Maone A, D’Avanzo B, ed. Recovery. Nuovi paradigmi per la salute mentale. Milano: Raffaello Cortina; 2015.


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