Vollständiger Titel
PNEI REVIEW
Verlag
FrancoAngeli
ISSN
2532-6147 (Gedruckte Zeitschrift)
2532-2826 (Online-Zeitschrift)
Nummer der Ausgabe
1
Andere Beschreibung der Ausgabe
1
Erscheinungsdatum der Ausgabe (YYYY/MM)
2018/03
Vollständiger Titel
Ontogenetica ed epigenetica del sistema immunitario nelle prime fasi della vita
Von (Autor)
Erste Seite
92
Letzte Seite
110
Sprache des Textes
Italienisch
Erscheinungsdatum
2018/03
Copyright
2018 FrancoAngeli srl
Vorwort
Il sistema immunitario inizia la sua ontogenesi in utero dove, per le fisiologiche necessità della gravidanza, si sviluppa secondo un profilo squilibrato in senso Th2, utile al corretto compimento della medesima e ad una nascita a termine. Una serie di fattori - relativi alla gravidanza, al tempo di gestazione, alle modalità del parto, al tipo di allattamento, al legame di attaccamento che si costruisce tra madre e bambino, all'esposizione a inquinanti, farmaci e ad alcuni vaccini, tramite meccanismi epigenetici - condiziona lo sviluppo del sistema immunitario, che raggiungerà caratteristiche simile a quelle dell'adulto solo alla fine dell'adolescenza. Il corretto funzionamento del sistema immunitario da adulto è largamente dipendente dall'assetto che esso acquisisce nelle prime fasi della vita.
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