THIS DOI METADATA WAS LAST UPDATED: 2024-01-10 22:51
Full Title
RICERCHE DI PSICOLOGIA
Publisher
FrancoAngeli
ISSN
0391-6081 (Printed Journal)
1972-5620 (Online Journal)
Journal Issue Number
2
Journal Issue Designation
2-3
Journal Issue Date (YYYY/MM)
2013/05
Full Title
Attività motoria e demenza
By (author)
First Page
483
Last Page
500
Language of text
Italian
Publication Date
2013/05
Copyright
2012 FrancoAngeli srl
Introduction or preface
Il significativo aumento della prevalenza della malattia di Alzheimer e delle demenze e l'insufficiente disponibilita di opzioni terapeutiche in grado di incidere sull'evoluzione della malattia ha sollecitato un maggior interesse della comunita scientifica per l'individuazione di strategie in grado di prevenire o rallentare l'evoluzione della demenza. E noto che l'attivita fisica e in grado di ridurre il rischio di numerose malattie croniche, di migliorare le capacita funzionali e di ritardare in questo modo la disabilita. Un'ampia messe di studi longitudinali ed un minor numero di trial clinici indica che l'esercizio fisico condotto sia in eta adulta che in eta piu avanzata e associato ad un ridotto rischio di declino cognitivo e di demenza. Se elevati livelli di attivita fisica sono correlati ad un piu significativo effetto protettivo, anche un'attivita moderata - come camminare a passo svelto 90 minuti alla settimana - riduce il rischio di compromissione cognitiva e di demenza. I benefici migliori di una regolare attivita fisica si sono osservati negli anziani affetti da patologie croniche, con ridotti livelli funzionali e con un piu elevato rischio di demenza. Anche nelle persone gia colpite dalla malattia l'attivita fisica migliora la fitness, le capacita funzionali e le prestazioni cognitive e riduce i sintomi psichiatrico- comportamentali ed i disturbi del sonno. Sul piano biologico l'attivita fisica sembra aumentare la produzione di fattori neurotrofici (in particolare il BDNF), la sinaptogenesi, il flusso ematico cerebrale ed il volume della corteccia prefrontale e dell'ippocampo; riduce inoltre i depositi di amiloide e i marker biologici della malattia di Alzheimer. .
Unstructured Citation
Abbott, R.D., White, L.R., Ross, G.W., Masaki, K.H., Curb, J.D., Petrovitch, H.
(2004). Walking and dementia in physically capable elderly men. JAMA, 292,
1447-1453.
https://doi.org/10.1001/jama.292.12.1447
Unstructured Citation
Alexopoulos, G.S. (2003). Vascular disease, depression and dementia. Journal of the American Geriatrics Society, 51, 1178-1180
Unstructured Citation
Alzheimer’s Disease International (2009). World Alzheimer Report 2009. London
Unstructured Citation
Andrieu, S., Aboderin, I., Baeyens, J.P., Beard, J., Benetos, A., Berrut, G., Brainin,
M., Cha, H.B., Chen, L.K., Du, P., Forette, B., Forette, F., Franco, A.,
Fratiglioni, L., Gillette-Guyonnet, S., Gold, G., Gomez, F., Guimaraes, R.,
Gustafson, D., Khachaturian, A., Luchsinger, J., Mangialasche, F., Mathiex-
Fortunet, H., Michel, J.P., Richard, E., Schneider, L.S., Solomon, A., & Vellas,
B. (2011). IAGG Workshop: health promotion program on prevention of
late onset dementia. The Journal of Nutrition Health and Aging, 15, 562-575
https://doi.org/10.1007/s12603-011-0142-1
Unstructured Citation
Barnes, D.E., Yaffe, K., Satariano, W.A., Tager, I.B. (2003). A longitudinal study
of cardiorespiratory fitness and cognitive function in healthy older adults.-
Journal of the American Geriatrics Society, 51, 459-465
https://doi.org/10.1046/j.1532-5415.2003.51153.x
Unstructured Citation
Barnes, D.E., & Yaffe, K. (2011). The projected effect of risk factor reduction on
Alzheimer’s disease prevalence. The Lancet Neurology, 10, 819-828.
https://doi.org/10.1016/S1474-4422(11)70072-2
Unstructured Citation
Brown, A.K., Liu-Ambrose, T., Tate, R., & Lord, S.R. (2009). The effect of
group-based exercise on cognitive performance and mood in seniors residing
in intermediate care and self-care retirement facilities: a randomized
controlled trial. British Journal of Sports Medicine, 43, 608-614
https://doi.org/10.1136/bjsm.2008.049882
Unstructured Citation
Cesa Bianchi, M., & Cristini, C. (2009). Vecchio sarà lei! Muoversi, pensare, comunicare. Napoli: Guida
Unstructured Citation
Chang, M., Jonsson, P.V., Snaedal, J., Bjornsson, S., Saczynski, J.S., Aspelund, T., Eiriksdottir, G., Jonsdottir, M.K., Lopez, O.L., Harris, T.B., Gudnason, V., & Launer, L.J. (2010). The Effect of Midlife Physical Activity on Cognitive Function Among Older Adults: AGES—Reykjavik Study. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 65A(12), 1369-1374.
Unstructured Citation
Churchill, J.D., Galvez, D., Colcombe, S., Swain, R.A., Kramer, A.F., & Greenogh,
W.T. (2002). Exercise, experience and the aging brain. Neurobiol Aging,
23, 941-955
https://doi.org/10.1016/S0197-4580(02)00028-3
Unstructured Citation
Colcombe, S.J., Erickson, K.I., Scalf, P.E., Kim, J.S., Prakash, R., McAuley, E.,
Elavsky, S., Marquez, D.X., Hu, L., & Kramer, A.F. (2006). Aerobic Exercise
Training Increases Brain Volume in Aging Humans. The Journals of Gerontology
Series A: Biological Sciences and Medical Sciences, 61(11), 1166-1170
https://doi.org/10.1093/gerona/61.11.1166
Unstructured Citation
Cotman, C.W., & Berchtold, N.C. (2002). Exercise: a behavioral intervention to
enhance brain health and plasticity. Trends Neurosci, 25(6), 295-301
https://doi.org/10.1016/S0166-2236(02)02143-4
Unstructured Citation
DeWeerdt, S. (2011). Activity is the best medicine. Nature, 475, S16-S17
https://doi.org/10.1038/475S16a
Unstructured Citation
Eggermont, L.H.P., & Scherder, E.J.A. (2006). Physical activity and behaviour in
dementia. A review of the literature and implications for psychosocial
intervention in primary care. Dementia, 5, 411-428
https://doi.org/10.1177/1471301206067115
Unstructured Citation
Erickson, K.I., Raji, C.A., Lopez, O.L., Becker, J.T., Rosano, C., Newman, A.B.,
Gach, H.M., Thompson, P.M., Ho, A.J., & Kuller, L.H. (2010). Physical
activity predicts gray matter volume in late adulthood. The Cardiovascular
Health Study. Neurology, 75, 1415-1422.
https://doi.org/10.1212/WNL.0b013e3181f88359
Unstructured Citation
Erickson, K.I., Voss, M.W., Prakash, R.S., Basak, C., Szabor, A., Chaddock, L.,
Kim, J.S., Heo, S., Alves, H., White, S.M., Wojcicki, T.R., Mailey, E., Vieira,
V.J., Martin, S.A., Woods, J.A., McAuley, E., & Kramer, A.F. (2011). Exercise
training increases size of hippocampus and improves memory. PNAS,
108(7), 3017-3022.
https://doi.org/10.1073/pnas.1015950108
Unstructured Citation
Ferrucci, L., Izmirilian, G., Phillips, C.L., Corti, M.C., Brock, D.B., & Guralnik, J.M. (1999). Smoking, physical activity and active life expectancy. American Journal of Public Health, 149, 645-653.
Unstructured Citation
Fiatarone, M.A., O’Neill, E.F., Ryan, N.D., Clements, K.M., Solares, G.R., Nelson,
M.E., Roberts, S.B., Kehayias, J.J., Lipsitz, L.A. & Evans, W.J. (1994).
Exercise training and nutritional supplementation for physical frailty in very
elderly people. The New England Journal of Medicine, 330, 1769-75.
https://doi.org/10.1056/NEJM199406233302501
Unstructured Citation
Fratiglioni, L., Paillard-Borg, S., & Winblad, B. (2004). An active and socially integrated
lifestyle in late life might protect against dementia. The Lancet Neurology,
3, 343-353
https://doi.org/10.1016/S1474-4422(04)00767-7
Unstructured Citation
Fratiglioni, L., & Qiu, C. (2011). Prevention of cognitive decline in ageing: prevention
as the target, delayed onset as the goal. The Lancet Neurology, 10,
778-779.
https://doi.org/10.1016/S1474-4422(11)70145-4
Unstructured Citation
Gill, T.M., Baker, D.I., Gottschalk, M., Peduzzi, P.N., Allore, H., Byers, A.
(2002). A program to prevent functional decline in physically frail, elderly
persons who live at home. The New England Journal of Medicine, 347, 1068-
1074.
https://doi.org/10.1056/NEJMoa020423
Unstructured Citation
Hassmen, P., & Koivula, N. (1997). Mood, physical working capacity and cognitive performance in the elderly as related to physical activity. Aging-Clinical and Experimental Research, 9, 136-142.
Unstructured Citation
Heyn, P., Abreu, B.C., & Ottenbacher, K.J. (2004). The effects of exercise training
on elderly persons with cognitive impairment and dementia: a meta-analysis.
Archives of Physical Medicine and Rehabilitation, 85, 1694-1704
https://doi.org/10.1016/j.apmr.2004.03.019
Unstructured Citation
Jack Jr, C.R., Knopman, D.S., Jagust, W.G.J., Shaw, L. M., Aisen, P. S., Weiner,
M. W., Petersen, C. R., & Trojanowski, J. Q. (2010). Hypothetical model of
dynamic biomarkers of the Alzheimer’s pathological cascade. The Lancet
Neurology, 9, 119-128.
https://doi.org/10.1016/S1474-4422(09)70299-6
Unstructured Citation
von Kanel, R., Mausbach, B.T., Dimsdale, J.E., Mills, P.J., Patterson, T.L., Ancoli-
Israel, S., Ziegler, M.G., Roepke, S.K., Harmell, A.L., Allison, M., & Grant,
I. (2011). Regular physical activity moderates cardiometabolic risk in
Alzheimer’s caregivers. Medicine & Science in Sports & Exercise, 43, 181-
189
https://doi.org/10.1249/MSS.0b013e3181e6d478
Unstructured Citation
Katzman, R. (1993). Views and reviews: education and the prevalence of Alzheimer’s
disease. Neurology, 43, 13-20
https://doi.org/10.1212/WNL.43.1_Part_1.13
Unstructured Citation
King, A.C., Baumann, K., O’Sullivan, P., Wilcox, S., & Castro, C. (2002). Effects
of moderate-intensity exercise on psychological, behavioral and emotional responses
to family caregiving: a randomized controlled trial. J Gerontol, 57,
M26-M36
https://doi.org/10.1093/gerona/57.1.M26
Unstructured Citation
Koehl, M., Meerlo, P., Gonzales, D., Rontal, A., Turck, F.W., & Abrous D.N.
(2008). Exercise-induced promotion of hippocampal cell proliferation requires
b-endorphin. FASEB J, 22(7), 2253-2262
https://doi.org/10.1096/fj.07-099101
Unstructured Citation
Kramer, A.F., Erickson, K.I. & Colcombe, S.J. (2006). Neural changes associated
with training. Exercise, cognition, and the aging brain. Journal of Applied
Physiology, 101, 1237-1242
https://doi.org/10.1152/japplphysiol.00500.2006
Unstructured Citation
Lampinen, P., Heikkinen, R.L., & Ruoppila, I. (2000). Changes in intensity of
physical exercise as predictors of depressive symptoms among older adults: an
eight-year follow-up. Prev Med, 30, 371-380.
https://doi.org/10.1006/pmed.2000.0641
Unstructured Citation
Larson, E.B. (2011). Brain and aging. Archives of Internal Medicine, 171(14),
1258-1259
https://doi.org/10.1001/archinternmed.2011.273
Unstructured Citation
Lautenschlager, N.T., Cox, K.L., Flicker, L., Foster, J.K., van Bockxmeer, F.M.,
Xiao, J., Greenop, K.R., & Almeida, O.P. (2008). Effect of physical activity
on cognitive function in older adults at risk for Alzheimer disease. A randomized
trial. JAMA, 300(9), 1027-1037.
https://doi.org/10.1001/jama.300.9.1027
Unstructured Citation
Liang, K.Y., Mintun, M.A., Fagan, A.M., Goate, A.M., Bugg, J.M., Holtzman,
D.M., Morris, J.C., Head, D. (2010). Exercise and Alzheimer’s disease biomarkers
in cognitively normal older adults. Annals of Neurology, 68, 311-318
https://doi.org/10.1002/ana.22096
Unstructured Citation
Mangialasche, F., Solomon, A., Winblad, B., Mecocci, P., & Kivipelto, M.
(2010). Alzheimer’s disease: clinical trials and drug development. The Lancet
Neurology, 9, 702-716.
https://doi.org/10.1016/S1474-4422(10)70119-8
Unstructured Citation
McCurry, S.M., Pike, K.C., Vitiello, M.V., Logsdon, R.G., Larson, E.B., & Teri,
L. (2011). Increasing walking and bright light exposure to improve sleep in
community-dwelling persons with Alzheimer’s disease: results of a randomized,
controlled trial. Journal of the American Geriatrics Society, 59(8), 1393-
402.
https://doi.org/10.1111/j.1532-5415.2011.03519.x
Unstructured Citation
Mead, G.E., Morley, W., Campbell, P., Greig, C.A., McMurdo, M., & Lawlor,
D.A. (2009). Exercise for depression. Cochrane Database of Systematic Reviews,
Issue 3. Art. No.: CD004366
https://doi.org/10.1002/14651858.CD004366.pub4
Unstructured Citation
Middleton, L.E, & Yaffe, K. (2010). Targets for the prevention of dementia. Journal of the Alzheimer’s Disease, 20, 915-924
Unstructured Citation
Nusselder, W.J., Looman, C.W.N., Franco, O.H., Peeters, A., Slingerland, A.S.,
& Mackenbach, J.P. (2008) The relation between non-occupational physical
activity and years lived with and without disability. Journal of Epidemiology
& Community Health, 62, 823-828
https://doi.org/10.1136/jech.2007.067165
Unstructured Citation
Olazarán, J., Muñiz, R., Reisberg, B., Peña-Casanova, J., del Ser, T., Cruz-
Jentoft, A. J., Serrano, P., Navarro, E., García de la Rocha, M. L., Frank, A.,
Galiano, M., Fernández-Bullido, Y., Serra, Y. A., González-Salvador, M.T. &
Sevilla, C. (2004). Benefits of cognitive-motor intervention in MCI and mild
to moderate Alzheimer disease. Neurology, 63, 2348-2353
https://doi.org/10.1212/01.WNL.0000147478.03911.28
Unstructured Citation
Patel, K.V., Coppin, A.K., Manini, T.M., Lauretani, F., Bandinelli, S., Ferrucci,
L., & Guralnik, J.M. (2006). Midlife physical activity and mobility in older
age: The InCHIANTI study. American Journal of Preventive Medicine, 31(3),
217-224.
https://doi.org/10.1016/j.amepre.2006.05.005
Unstructured Citation
Paterson, D.H., & Warburton, D.E. (2010). Physical activity and functional limitations in older adults: a systematic review related to Canada’s Physical Activity Guidelines. International Journal of Behavioral Nutrition and Physical Activity, 11, 7-38.
Unstructured Citation
Penninx, B.W., Messier, S.P., Rejeski, W.J., Williamson, J.D., DiBari, M.,
Cavazzini, C., Applegate, W.B., & Pahor, M. (2001). Physical exercise and
the prevention of disability in activities of daily living in older persons with
osteoarthritis. Archives of Internal Medicine, 161(19), 2309-2316.
https://doi.org/10.1001/archinte.161.19.2309
Unstructured Citation
Pereira, A.C., Huddleston, D.E., Brickman, A.M., Sosunov, A.A., Hen, R.,
McKhann, G.M., Sloan, R., Gage, F.H., Brown, T.R., &, Small, S.A. (2007).
An in vivo correlate of exercise-induced neurogenesis in the adult dentate
gyrus. PNAS, 104, 5638-5643.
https://doi.org/10.1073/pnas.0611721104
Unstructured Citation
Plassman, B.L., Williams, J.W., Burke, J.R., Holsinger, T., & Benjamin, S.
(2010). Systematic review: factors associated with risk for and possible prevention
of cognitive decline in later life. Annals of Internal Medicine, 153,
182-193.
https://doi.org/10.7326/0003-4819-153-3-201008030-00258
Unstructured Citation
Podewils, L.J., Guallar, E., Kuller, L.H., Fried, L.P., Lopez, O.L., Carlson, M., &
Lyketsos, C.G. (2005). Physical activity, APOE genotype, and dementia risk:
findings from the Cardiovascular Health Cognition Study. American Journal
of Epidemiology, 161, 639-51
https://doi.org/10.1093/aje/kwi092
Unstructured Citation
Podewils, L.J., & Guallar, E. (2006). Mens sana in corpore sano. Annals of Internal
Medicine, 144, 135-136
https://doi.org/10.7326/0003-4819-144-2-200601170-00011
Unstructured Citation
Potter, R., Ellard, D., Rees, K., & Thorogood, M. (2011). A systematic review of
the effects of physical activity on physical functioning, quality of life and depression
in older people with dementia. International Journal of Geriatric
Psychiatry, 26(10), 1000-1011.
https://doi.org/10.1002/gps.2641
Unstructured Citation
Ravaglia, G., Forti, P., Lucicesare, A., Pisacane, N., Rietti, E., Bianchin, M., & Dalmonte, E. (2008). Physical activity and dementia risk in the elderly. Findings from a prospective Italian study. Neurology, 70, 1768-1794.
Unstructured Citation
Rogers, R.L., Meyer, J.S., & Mortel, K.F. (1990). After reaching retirement age physical activity sistains cerebral perfusion and cognition. Journal of the American Geriatrics Society, 38, 123-128
Unstructured Citation
Rolland, Y., Pillard, F., Klapouszczak, A., Reynish, E., Thomas, D., Andrieu, S., Riviere, D., & Vellas, B. (2007). Exercise program for nursing home residents with Alzheimer’s disease: a 1-year randomized controlled trial. Journal of the American Geriatrics Society, 55, 158-165
Unstructured Citation
Rovio, S., Kåreholt, I., Helkala, E.L., Viitanen, M., Winblad, B., Tuomilehto, J.,
Soininen, H., Nissinen, A., & Kivipelto, M. (2005). Leisure-time physical
activity at midlife and the risk of dementia and Alzheimer’s disease. The Lancet
Neurology., 4, 705-11.
https://doi.org/10.1016/S1474-4422(05)70198-8
Unstructured Citation
Savica, R., & Petersen, R.C. (2011). Prevention of dementia. Psychiatric Clinics
of North America, 34, 127-145
https://doi.org/10.1016/j.psc.2010.11.006
Unstructured Citation
Scarmeas, N., & Stern, Y. (2003). Cognitive reserve and lifestyle. Journal of Clinical and Experimental Neuropsychology, 5, 625-633
Unstructured Citation
Smith, P.J., Blumenthal, J.A., Hoffman, B.M., Cooper, H, Strauman, T.A.,
Welsh-Bohmer, K., Browndyke, J.N., & Sherwood, A. (2010). Aerobic exercise
and neurocognitive performance: a meta-analytic review of randomized
controlled trials. Psychosomatic Medicine, 72, 239-252
https://doi.org/10.1097/PSY.0b013e3181d14633
Unstructured Citation
Sofi, F., Valecchi, D., Bacci, D., Abbate, R., Gensini, G.F., Casini, A., & Macchi,
C. (2010). Physical activity and risk of cognitive decline: a meta-analysis of
prospective studies. Journal of Internal Medicine, 269, 107-117
https://doi.org/10.1111/j.1365-2796.2010.02281.x
Unstructured Citation
Stuck, A.E., Walhert, J.M., Nikolaus, T., Bula, C.J., Holman, C., & Beck, J.C.
(1999). Risk factors for functional status decline in community-living elderly
people: a systematic literature review. Social Science & Medicine,48, 445-
469.
https://doi.org/10.1016/S0277-9536(98)00370-0
Unstructured Citation
Sun, Q., Townsend, M.K., Okereke, O.I., Franco, O.H., Hu, F.B., & Grodstein, F.
(2010). Physical activity at midlife in relation to successful survival in women
at age 70 years or older. Archives of Internal Medicine, 170(2), 194-201
https://doi.org/10.1001/archinternmed.2009.503
Unstructured Citation
Taaffe, D.R., Irie, F., Masaki, K.H., Abbott, R.D., Petrovitch, H., Webster Ross, G., & White, L.R. (2008). Physical activity, physical function, and incident dementia in elderly men: the Honolulu–Asia Aging Study. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences, 63(5), 529- 535.
Unstructured Citation
Tan, Z.S., Beiser, A.S., Au, R., Kelly-Hayes, M., Vasan, R.S., Auerbach, S., Murabito, J., Pikula, A., Wolf, P.A., & Seshadri, S.S. (2010). Physical activity and the risk of dementia: the Framingham Study. Alzheimer’s Association International Conference on Alzheimer’s Disease, Abstract 01-01-03.
Unstructured Citation
Vercambre, M.N., Grodstein, F., Manson, J.A.E., Stampfer, M.J., Kang, J.H.
(2011). Physical activity and cognition in women with vascular conditions.
Archives of Internal Medicine, 171(14), 1244-1250
https://doi.org/10.1001/archinternmed.2011.282
Unstructured Citation
Verdelho, A., Madureira, S., Ferro, J.M., Baezner, H., Blahak, C., Poggesi, A.,
Hennerici, M., Pantoni, L., Fazekas, F., Scheltens, P., Waldemar, G., Wallin,
A., Erkjniuntti, T., & Inzitari, D. (2012). Physical activity prevent progression
for cognitive impairment and vascular dementia. Stroke, 43(12), 3351-3355
https://doi.org/10.1161/STROKEAHA.112.661793
Unstructured Citation
Verghese, J., Lipton, R.B., Katz, M.J., Hall, C.B., Derby, C.A., Kuslansky, G.,
Ambrose, A.F., Sliwinski, M., & Buschke, H. (2003). Leisure activities and
the risk of dementia in the elderly. The New England Journal of Medicine,
348, 2508-16.
https://doi.org/10.1056/NEJMoa022252
Unstructured Citation
Weuve, J., Kang, J.H., Manson, J.E., Breteler, M.M.B., Ware, J.H., & Grodstein,
F. (2004). Physical activity including walking and cognitive function in older
women. JAMA, 292, 1454-1461.
https://doi.org/10.1001/jama.292.12.1454
Unstructured Citation
WHO (2002). Reducing risks, promoting healthy life. World Health Report 2002
Unstructured Citation
WHO (2010). Global recommendations on physical activity for health. World Health Organization
Unstructured Citation
Williams, C.L., & Tappen, R.M. (2007). Effect of Exercise on Mood in Nursing
Home Residents With Alzheimer’s Disease. American Journal of Alzheimer's
Disease and Other Dementias, 22, 389-397
https://doi.org/10.1177/1533317507305588
Unstructured Citation
Winchester, J., Dick, M.B., Gillen, D., Reed, B., Miller, B., Tinklenberg, J., Mungas,
D., Chui, H., Galasko, D., Hewett, L., & Cotman, C.W. (2013). Walking
stabilizes cognitive functioning in Alzheimer’s disease across one year. Arch
Gerontol Geriatr, 56(1), 96-103
https://doi.org/10.1016/j.archger.2012.06.016
Unstructured Citation
Yaffe, K., Barnes, D., Nevitt, M., Lui, L.Y., & Covinsky, K. (2001). A prospective
study of physical activity and cognitive decline in elderly women. Archives
of Internal Medicine, 161, 1703-1708
https://doi.org/10.1001/archinte.161.14.1703